Jamie-Lynn Sigler slams ‘healthy and perfect’ people for ‘abusing’ Ozempic: ‘It’s upsetting’

Jamie-Lynn Sigler is upset with the current Ozempic trend.

The actress, 42, called out “healthy and perfect” people for abusing the weight loss drug in the Tuesday episode of her and Christina Applegate’s “MeSsy” podcast, admitting that the current fad has left her “a little triggered.”

“I’m annoyed at myself that I’m admitting this,” said Sigler, who shares Applegate’s multiple sclerosis diagnosis. “It’s upsetting me. I wish I didn’t care.”

While she and Applegate opened up about their own experiences with body image issues and eating disorders, the “Sopranos” alum admitted that the drug has helped her friends who she’s seen “struggle with their weight for a very, very, very long time.”

“I’ve seen it give them a lot and I am so happy for them,” she said.

Sigler added, “I have also seen friends of mine, who were beautiful and healthy and perfect, abusing it, and it’s upsetting me.”

Sigler, who struggled with an eating disorder in the late ’90s and later became a spokesperson for the National Eating Disorders Association, also said that the rise in users taking the drug seemingly signifies a setback in the body positivity movement.

“It felt like we were on this road to solidifying body positivity, and every shape and size and color, and everyone’s looking the same now,” she said.

Applegate, 52, agreed with her co-host adding that use of the drug has left people “fading away.”

“For women out there listening, the thinner your face is, the older you look, okay?” she joked, but quickly cleaned it up. “Not that looking old is bad! Aging gracefully is beautiful.”

In 2022, the “Dead to Me” star revealed she’d gained 40 pounds and was unable to walk without a cane after receiving her MS diagnosis in 2021. During the podcast episode, Applegate also opened up about accepting the more recent changes in her body that stemmed from the disease.

“I don’t look in mirrors. I have writing all over my mirrors in my bathroom so that I don’t look in them,” she said. “Because I will like fall on the ground and cry. That’s how I feel now.”

Applegate also reflected on her previous experience with anorexia as a teen actress starring in “Married With Children,” but says now, “I don’t need to be thin.”

Instead, she’d rather fit into her old clothes again.

“I’m not working. I have a closet full of clothes that I can’t wear, and I have no money coming in. I don’t want to spend money on new clothes. I would just like to wear the ones that I already own,” she said.