Ryan Seacrest sparks concern with ‘Wheel of Fortune’ appearance: ‘No way’ that’s him

Ryan Seacrest fans are concerned about the “Wheel of Fortune” host after a clip from the show went viral on Instagram last week.

In the Jan. 23 footage, the 51-year-old congratulated Vanna White on her recent marriage to John Donaldson earlier this month.

“That’s Ryan Seacrest??? No way. Absolutely no way,” one fan wrote via X.

Another claimed, “Ryan Seacrest looks like an entirely different human.”

Some theorized the multi-hyphenate was being portrayed by an actor and asked the “real Ryan Seacrest [to] step forward,” noting, “It doesn’t even sound like Ryan never mind not looking like him.”

One netizen wrote, “Ryan Seacrest looks like a shell of his former self. What in the name of Ozempic is happening?”

Others came to Seacrest’s defense, insisting “he’s just older.”

Many compared his slimmed-down appearance to how Chadwick Boseman looked during his private cancer battle.

“[Boseman] was relentlessly body shamed while he was battling illness privately and everyone who was talking about him felt like crap when he left this Earth [in 2020],” one fan wrote.

“Idk if Ryan Seacrest is ill or not but making fun of his appearance instead of praying for him or just being quiet is a choice.”

Seacrest’s rep did not immediately respond to Page Six’s request for comment.

The Emmy winner sparked similar comments in July 2025 when he posted photos of life “lately” looking noticeably thinner.

Four months later, Seacrest showed off his muscles in a video doing bicep curls in a T-shirt and shorts.

“The trick is to wear a t-shirt two sizes too small,” he joked in the caption of the November 2025 workout.

The previous year, Seacrest admitted to “over-exercising, eating better, over-training” ahead of turning 50.

“I’m doing everything I can to feel like I’m not 50,” he told Entertainment Tonight in December 2024. “Anything I can do to make myself feel 29 again.”

Seacrest’s regimen at the time included “lots of muscle recovery, cold plunging and steaming.”