See the Cast of The Twits Side-by-Side with the Zany Characters They Play

Emilia Clarke as Pippa

It wouldn’t be The Twits without the courageous spirit of Pippa, voiced by Clarke.

The actress joins the cast as the narrator. In the Netflix adaptation, Pippa helps describe the fight against the Twits’ reign of mischief and terror, serving as a moral compass amid the chaos.

Clarke is newer to voice work and is best known for her starring role in Game of Thrones.

Natalie Portman as Mary Muggle-Wump

Portman brings some warmth to The Twits as Mary Muggle-Wump, one half of the monkey duo long tormented by Mr. and Mrs. Twit.

In Dahl’s original story, the Muggle-Wumps are clever and resourceful, using their smarts to turn the tables on their cruel captors. The Oscar-winning actress is most known for her work in Star Wars, Black Swan and Thor.

Johnny Vegas as Jim Twit

Vegas takes on the gloriously grotesque role of Jim Twit, the foul-tempered prankster at the heart of the classic tale.

Known for his brash comedic style, the British actor seems tailor-made for the part of the bearded bully who delights in tormenting everyone around him — especially his wife. In the Netflix film, Mr. Twit is reimagined as a chaotic ringleader whose greed and cruelty spiral into mayhem as he and Credenza plot to take over their town.

Vegas shared The Hollywood Reporter’s cast update post on his Instagram on Aug. 18, 2025, being sure to mention the plot and the other actors who would be joining him on set. The actor has been in a slew of BBC projects, including Ideal and Still Open All Hours.

Margo Martindale as Credenza Twit

Martindale plays Jim’s better half, Credenza, bringing her signature gravitas to Dahl’s odious creation. In the film, Credenza runs the bizarre amusement park of Twitlandia alongside her husband — delighting in dirty pranks, filth and cruelty along the way.

Johnston said they reimagined Credenza not merely as a “hag” but as “diva or rock star who never made it.”

In a 2025 interview with Litchfield Magazine, Martindale described the voice work as “wildly fun, but tiring,” noting she recorded over a two-year stretch and that “the whole thing is your voice, so it takes that much more push.”

The actress has had a long career in Hollywood, most notably taking on roles in Justified, August: Osage County and The Good Wife.

Jason Mantzoukas as Mayor Wayne John John-John

Mantzoukas joins the cast as Mayor Wayne John John-John, stepping into the political chaos as the city’s loudly inept leader.

In the story, the Twits escalate their mischief from pranks to power plays — even running for government — and Mayor Wayne becomes the absurd foil in their rise.

The actor is well known for his unique comedic style, which he brought to his beloved roles in Brooklyn Nine-Nine and The Good Place.

Alan Tudyk as The Sweet-Toed Toad

Tudyk brings his vocal versatility to the movie as The Sweet-Toed Toad, one of the story’s most peculiar creatures. Known for his work in Disney and Pixar favorites like Encanto and Frozen, Tudyk adds another unforgettable animal to his résumé with this slime-covered amphibian.

In Netflix’s adaptation, the Sweet-Toed Toad is one of several magical animals who band together to stop the Twits’ reign of chaos. The character’s oddball charm and offbeat humor turns even the slimiest creature into a scene-stealer.

Maitreyi Ramakrishnan as Beesha

Maitreyi Ramakrishnan lends her voice to Beesha in The Twits. Best known for her breakout role as Devi in Netflix’s Never Have I Ever, Ramakrishnan steps into a new kind of chaos here — one filled with magical animals and over-the-top mischief.

In the film, Beesha is one of the brave young heroes who stand up to Mr. and Mrs. Twit’s reign of nastiness, helping rally the townspeople and creatures against their grotesque rule.

Nicole Byer as Beverly Onion

Nicole Byer joins The Twits as Beverly Onion, one of the film’s original characters created for Netflix’s adaptation. Known for her time on Nailed It! and her vibrant voice work in animated hits like The Ghost and Molly McGee and Tuca & Bertie, Byer adds a burst of eclectic charm to the animated film.

While she doesn’t appear in the original book, the character helps expand the world of Twitlandia — serving as a colorful figure caught in the crossfire of the Twits’ mischief and mayhem.

Timothy Simons as Marty Muggle-Wump

Marty Muggle-Wump is part of the clever monkey duo determined to outsmart their vile captors, perfectly voiced by Timothy Simons.

Known for his Emmy-nominated turn as Jonah Ryan on HBO’s Veep, Simons brings his trademark deadpan delivery and excellent comedic timing to the ever-scheming Marty — a character whose smarts and sarcasm are key to taking down the Twits’ tyranny.

Rebecca Wisocky as Dee Dumdie-Dungle

Rebecca Wisocky, best known for her role as Hetty Woodstone on CBS’s Ghosts, voices Dee Dumdie-Dungle in The Twits.

Wisocky brings a theatrical bite to the new character — one created specifically for Netflix’s adaptation.