Savannah Guthrie slams speculation her family was involved in mom Nancy’s disappearance

Savannah Guthrie hit back at the “cruel … whispers and innuendos” that her family members were involved in mom Nancy Guthrie’s disappearance.

In her first interview since the 84-year-old vanished, Guthrie told Hoda Kotb that the speculation “piles pain upon pain.”

She added, “It’s unbearable. … There are no words. I don’t understand, and I’ll never understand.”

Savannah went on to defend her siblings — Camron Guthrie and Annie Guthrie — as well as her sister’s husband, Tommaso Cioni.

“No one took better care of my mom than my sister and brother-in-law,” the journalist insisted. “And no one protected my mom more than my brother.”

The “cooperative and gracious” family members, notably, were cleared as suspects on Feb. 16.

Savannah went on to describe the days she spent in a “blur” with loved ones in Arizona while awaiting updates.

“We had to move houses many times because people came and not everyone is respectful, unfortunately,” she recalled. “There was a night we had to leave in the dark in the desert holding hands … and get into a car waiting for us.”

Savannah noted that “the people outside were closing in.”

The Guthries “found a place that was safe and then couldn’t really leave too much,” spending their time “crying and praying.”

Savannah, who cried throughout the emotional interview, issued an apology to Nancy and admitted she blames herself.

“I don’t know that it’s because she’s my mom and somebody thought, ‘Oh, that lady has money, we can make a quick buck,’ [but] that would make sense,” she said.

The possibility, Savannah confessed, is “too much to bear.”

Nancy was last seen at her Tucson, Ariz., home on Jan. 31, disappearing overnight.

Savannah found out her mom was missing when Annie called her and has been living in “disbelief and chaos” ever since.

On Thursday, Savannah shared new chilling details from the case, including how the home appeared on Feb. 1 — back doors propped open and blood on the porch — and how many ransom notes she believes are legit.

The investigation remains ongoing.